The emergence of the severe acute respiratory syndrome coronavirus 2 virus in late 2019 precipitated a global health emergency that contributed to more than 7 million reported deaths globally as of 19 January 2024 (ref. 1) and an estimated 18.2 million excess deaths between 1 January 2020 and 31 December 2021 (ref. 2). The coronavirus disease 2019 (COVID-19) pandemic, requiring urgent international intervention, led to an accelerated pace of research and development of multiple safe, effective COVID-19 vaccines, which were first authorized for emergency use in December 20203. The expeditious vaccine development and limited availability resulted in serious challenges in the equitable global distribution of vaccines, coupled with vaccine-related misinformation and mistrust of the science behind vaccine safety4.
Vaccine hesitancy5, pandemic fatigue6 and vaccine fatigue, defined as the ‘inertia or inaction toward vaccine information or instruction due to perceived burden and burnout’7, continue to present challenges to vaccine uptake in 2023. Although COVID-19 has been deprioritized as a substantial public health threat since 2023, the virus strains continue to circulate and, in some settings, lead to new increases in hospitalization and intensive care unit admission1. The potential impact of vaccine hesitancy on confidence in booster doses remains substantial8. In addition, documented spillover effects on routine immunization pose a threat for the reemergence of some childhood and adult vaccine-preventable diseases9,10.
In this Brief Communication, the fourth study in a series of annual global surveys across 23 countries (Brazil, Canada, China, Ecuador, France, Germany, Ghana, India, Italy, Kenya, Mexico, Nigeria, Peru, Poland, Russia, Singapore, South Africa, South Korea, Spain, Sweden, Türkiye, the United Kingdom and the United States)11,12,13, we report perspectives of adults in the general public on COVID-19 and